HCP Exclusive Products
Glucose Stabilizer
Maintenance metabolic support for long-term stability
Capsules | Supplement | Up to 2 times daily
Designed for sustainable meal-level modulation and long-term metabolic balance.
Best suited for:
- Everyday post-meal glucose support
- Long-term metabolic well-being and healthy ageing
- Maintenance phases after intensive protocols
- Patients preferring capsule format
Daily steadiness. Appetite regulation. Long-term use.
Carb Fence
High-intensity meal-level intervention for structured protocols
Liquid formula | Medical Food | Up to 3 times daily
Designed for higher per-meal modulation in defined clinical settings.
Best suited for patients with nutritional management needs during:
- Weight‑loss phases with lean‑mass preservation
- A1C reduction strategies
- Post‑GLP‑1 taper support
- Higher‑appetite and central adiposity management
Stronger per-meal modulation. Structured protocol use.
Early Access Program
Be among the first to implement Carb Fence in clinical practice
Carb Fence is designed for nutritional management within structured clinical protocols addressing metabolic load and weight management.
Carb Fence can be integrated into care plans to support:
- Healthy glucose metabolism
- Appetite regulation and post-meal fullness
- Structured weight management programs
- Patients transitioning off GLP-1–based therapies
Metabolic Stress: The Upstream Driver of Metabolic Disease
Metabolic syndrome is the diagnosis. Metabolic stress is the mechanism.
In modern food systems characterized by fast energy, high reward, and constant availability, repeated high-load meals drive cumulative metabolic stress. Over time, this contributes to obesity, type 2 diabetes, and cardiometabolic disease.
Metabolic Health Remains Unsolved
1) Lifestyle Adaptation
Effective in principle, difficult to sustain in modern food environments. Requires high adherence and long-term behavioral discipline.
2) Systemic Interventions
Clinically appropriate for defined populations. Systemic by design and typically ongoing.
The Third Strategy: Meal-Level Input Modulation
SIGRID’s approach represents a third strategy, powered by patented SiPore® technology. Our products are designed to be taken with everyday meals.
They work locally in the gut to support a reduced digestive impact from carbohydrates and fats during digestion.
Less impact per meal. Metabolic stability over time.
SiPore®: Gut-Local Modulation of Metabolic Load
SiPore® is a patented, precision-engineered silica material with a precisely controlled pore structure. It is designed to function locally in the small intestine during digestion to reduce per-meal metabolic load.
Non-systemic. Not absorbed.
1) Enzyme Entrapment in the Small Intestine
During digestion, SiPore® particles mix with food and digestive enzymes. The engineered pores entrap a portion of alpha-amylase and lipase.
2) Reduced Carbohydrate and Fat Breakdown
Reduced enzyme activity slows the breakdown of carbohydrates and fats.
3) More Gradual Energy Absorption
Slower digestion results in a more gradual release of energy into the bloodstream.
4) Lower Post-Meal Metabolic Load
Each meal delivers a lower metabolic impact, supporting steadier post-meal physiology.
Mechanism-Led. Clinically Evaluated.
SiPore® technology has been evaluated across pre-clinical and clinical studies.
Primary Protocols
Structured Use Frameworks for Meal-Level Metabolic Modulation
SIGRID’s products, powered by patented SiPore® technology, can be integrated into structured care frameworks to support weight management, post-meal glucose balance, appetite regulation, and metabolic stability.
Weight-Loss Protocol
Lean-Mass–Supportive Fat Reduction
Designed for individuals with overweight or obesity, elevated appetite, and central adiposity.
Carb Fence supports lower per-meal metabolic load during active fat-loss phases, promoting post-meal satiety and supporting metabolic stability as part of broader nutrition and lifestyle plans.
Post-GLP-1 Taper Protocol
Appetite and Post-Meal Stabilization
For individuals tapering GLP-1–based therapies who require structured meal-level support.
Carb Fence provides gut-local modulation to support appetite regulation and steadier post-meal glucose patterns during transition phases.
Pre-Diabetic A1C-Lowering Protocol
Targeted Glycemic Stabilization
For individuals with impaired glucose regulation or elevated A1C within non-diagnostic ranges.
Carb Fence helps moderate post-meal metabolic load and supports healthy glucose metabolism when used consistently within structured care frameworks.
Menopause Metabolic Stability Protocol
Abdominal Fat and Energy Regulation
For women experiencing metabolic shifts during hormonal transitions, including increased abdominal fat and cravings.
Meal-level modulation supports steadier energy delivery and appetite regulation during these phases.
PCOS Weight & Glucose Management Protocol
Insulin-Sensitive Metabolic Support
For women with insulin resistance patterns, elevated appetite, and central fat accumulation.
Carb Fence supports appetite control and post-meal metabolic balance as part of comprehensive PCOS nutrition strategies.
Postpartum Metabolic Reset
Gradual Recovery and Appetite Recalibration
For women navigating postpartum metabolic shifts, including weight retention and fluctuating appetite.
A structured approach may begin with Glucose Stabilizer for daily metabolic support and incorporate Carb Fence during higher metabolic-load meals.
For women who are breastfeeding, use should be evaluated in consultation with a healthcare professional.
Longevity & Healthy Aging Protocol
Daily Metabolic Stability
For adults prioritizing long-term metabolic resilience.
Glucose Stabilizer provides ongoing meal-level support to help maintain stable energy patterns and reduce cumulative metabolic load over time.
Frequently Asked Questions
No. SiPore® acts locally in the small intestine during digestion and is not absorbed into the bloodstream. It passes through the gastrointestinal tract.
SiPore® is a patented, precision-engineered silica material with a precisely defined pore structure designed for digestive enzyme entrapment.
Unlike dietary fiber, which primarily adds bulk or influences fermentation, SiPore® is engineered to physically interact with digestive enzymes through a mechanical mode of action.
SiPore® is designed to entrap a portion of alpha-amylase and lipase in the small intestine, reducing the rate of carbohydrate and fat breakdown.
No. SiPore® supports meal-level modulation through digestive enzyme entrapment.
It slows the breakdown of carbohydrates and fats but does not fully inhibit nutrient digestion or absorption.
Yes. SiPore® acts locally in the gut and does not have systemic exposure. It is designed to complement, not replace, pharmacologic therapies.
Yes. Structured meal-level modulation may help stabilize appetite and post-meal glucose during tapering phases.
SiPore® technology has been evaluated in multiple clinical studies and demonstrated a strong safety and tolerability profile.
Yes. It is designed to complement diet and behavioral strategies by reducing the metabolic impact of individual meals.