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SiPore® Early Access Clinical Pilot

Bring Meal-Level Metabolic Support Into Your Practice

Apply for early access to SiPore® Liquid, a gut-local, non-systemic approach designed to support steadier post-meal metabolic patterns and appetite stability.

Participating practices receive pilot product access, implementation resources, protocol guidance, Practitioner Hub onboarding, and optional CGM workflow support.

Apply for Early Access

HCP only • Limited onboarding • Pilot product included

Why Practices Are Exploring SiPore®

A Meal-Level Solution

SiPore® offers a non-systemic, meal-level approach designed to support steadier post-meal metabolic patterns during digestion.

CGM-Visible Outcomes

Supports workflows focused on postprandial glucose patterns, glycemic variability, and Time-In-Range (TIR).

Easy to Integrate

Designed to fit into existing metabolic health, longevity, weight management, and CGM-based care workflows.


Same Meal. Different Metabolic Response.

Modern meals are often digested rapidly, creating sharp spikes and crashes in glucose and energy that can drive cravings, hunger, and post-meal fatigue.

SiPore® is designed to slow carbohydrate and fat digestion during the meal process by temporarily entrapping digestive enzymes involved in digestion. This helps support a more gradual metabolic response after eating, which many users experience as:

✓ More stable post-meal energy
✓ Reduced cravings and snacking
✓ Longer-lasting fullness
✓ Fewer post-meal dips and crashes


Unlike systemic approaches, SiPore® works locally in the gut during digestion and does not enter the bloodstream.

What Participating Practices Receive

The pilot is designed to support structured, real-world implementation within metabolic health and longevity-focused practices.

Included in the Pilot

✓ 14-day SiPore® Liquid supply for up to four pilot participants

✓ Practitioner Hub access with protocols, educational tools, and scientific resources

✓ Clinical implementation guidance and onboarding support

✓ Optional CGM workflow integration and upload system

✓ Complimentary case of SiPore® Liquid upon successful pilot completion

How the Clinical Pilot Works

Step 1 – Request Account

Submit your professional and practice information in the form below to request an account.

Step 2 – Complete Wholesale Application

After submitting your request, you will receive a wholesale application by email. Complete and submit the application to begin the eligibility review process.

Step 3 – Eligibility Review

SIGRID reviews your licensure and practice information to verify eligibility.

Step 4 – Track Outcomes

Approved applicants receive pilot product, onboarding guidance via email, and Practitioner Hub access.


Apply to Join the Clinical Pilot

Selected practices receive pilot product access, implementation support, and Practitioner Hub onboarding for evaluating SiPore® Liquid in real-world metabolic health workflows.